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From Crown Bioscience & World Organoid Research Day+ 2024
Watch Now and Win the chance of a free pair of tickets to
World Organoid Research Day+ in 2024!
Don't miss the opportunity to view a transformative talk by Liza Wijler, an authority in the field of organoid drug discovery. In this crucial discussion on Pan-cancer 'Assay-ready' Organoid Drug Screening, you will delve deep into the innovations that are setting new standards for preclinical anticancer drug screening. You'll learn about:
Matched Model Pairs and Patient-Derived Xenografts
and Organoids Biobanks.
Functional Screening of Patient-Derived Organoids
Using High-Content Imaging
Cancer Organoid Screening: Bridging Reproducibility and Clinical Relevance in Drug Discovery
Cancer Research's Next Big Thing: A Deep Dive into Organoid Screening
By providing more physiologically relevant models, 3D cell cultures can bridge the gap between in vitro and in vivo models. Despite several options for 3D in vitro systems, the choice is not always straightforward. It largely depends on the biological question/s. This blog post examines key differences between spheroid and organoid models, so that you can make the best choice for your specific needs.
Our biobank offers over 200 patient-derived organoid (PDO) models for six oncological indications. Additionally, we have patient-matched normal models available for four indications, as well as patient-matched primary and metastatic models. Furthermore, we provide irritable bowel disease (IBD) PDO models for testing anti-inflammatory treatments and regenerative medicine approaches
The use of more clinically relevant preclinical models can help to reduce anticancer drug attrition rates by providing better understanding. This blog post explores the value of adult stem cell-derived 3D in vitro tumor organoids in drug discovery, particularly in identifying anticancer agents with improved translational potential, as highlighted in recent peer-reviewed publications.
Don't miss this exclusive opportunity to gain invaluable insights from one of the authors of our pioneering publication on cancer pharmacology; learn about the transformative potential of a living biobank with over 550 matched pairs of patient-derived xenografts and organoids, and how it is revolutionizing approaches in high-throughput screening, immune therapies, imaging, and overcoming limitations in traditional drug development models.
From Crown Bioscience & World Organoid Research Day+ 2024
Watch Now and Win the chance of a free pair of tickets to
World Organoid Research Day+ in 2024!
World Organoid Research Day+
In person. Cambridge, U.K
Organoid and Organ-on-a-chip talks on both days. WORD+ tickets fund research & research ticket attendees could win £1000 for their lab too.